The big cause of this problem is the publication and funding processes available to scientists. It's all very competitive, and the people who have the money don't want to waste it on studies that aren't producing the right results. This creates a conflict of interests, scientists tend to be very passionate about their work. There was a recent study of 2,047 papers on PubMed that found that two-thirds of retracted papers were down to scientific misconduct, not error.
This defeats the purpose of science. We're meant to be working to progress our knowledge as a species, not for our own personal gains. You can see comments from the people who were at the debate under twitter #solo12fraud (currently number 1 trend, hooray for science!)
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